하고초(夏枯草)에서 추출한 Ursolic acid의파골세포 분화 억제 효과

• Published in: 대한한방부인과학회지 Vol. 27; no. 2; pp. 59 - 70
• Main Authors: 허자경, Ja Kyung Heo, 황덕상, Deok Sang Hwang, 이진무, Jin Moo Lee, 이창훈, Chang Hoon Lee, 장준복, Jun Bock Jang, 이경섭, Kyung Sub Lee
• Format: Journal Article
• Language: Korean
• Published: 대한한방부인과학회 25.05.2014
• Subjects: C-Fos; NFATc1; OSCAR; Osteoclast; Prunella Vulgaris; TRAP; Ursolic Acid

This study was conducted to evaluate the inhibitory effect of ursolicacid from Prunella vulgaris on osteoclast differentiation. Methods: MTT-assay was performed to estimate cytotoxicity of ursolic acidfrom Prunella vulgaris in BMMs stimulated with M-CSF. TRAP staining, TRAPactivity and Real-time PCR...