크론병 환자에서 Azathioprine 치료 중 발생한 다형성 지방육종

• Published in: The Korean journal of gastroenterology Vol. 62; no. 4; pp. 248 - 252
• Main Authors: 안수민, Soo Min Ahn, 서승오, Seong O Suh, 오유미, Yu Mi Oh, 윤창용, Chang Yong Yun, 심형훈, Hyoung Hun Sim, 박채아, Chae A Park, 송철민, Cheol Min Song, 배지윤, Ji Yoon Bae
• Format: Journal Article
• Language: Korean
• Published: 대한소화기학회 30.10.2013
• Subjects: Azathioprine; Crohn disease; Liposarcoma
• ISSN: 1598-9992

Azathioprine is frequently used for the treatment of inflammatory bowel diseases (IBD) such as Crohn`s disease and ulcerative colitis. Lymphomas, squamous cell carcinomas, and undifferentiated pleomorphic sarcomas have been reported among patients receiving azathioprine therapy. Herein, we report a case of pleomorphic liposarcoma of chest wall which occurred in a 44-year-old man with Crohn`s disease taking azathioprine. He was diagnosed with Crohn`s disease 3 years ago after suffering from abdominal pain and hematochezia for 12 years. He had been taking 50 mg of azathioprine per day for 23 months when he visited the thoracic and cardiovascular surgery clinic due to right chest palpable mass that had rapidly grown during the past 2 months. Excisional biopsy was performed and the mass was diagnosed as pleomorphic liposarcoma. Therefore, he underwent radical excision of the right chest wall mass, which measured 11.0×6.5 cm in size. He is scheduled to receive radiation therapy and chemotherapy. (Korean J Gastroenterol 2013;62:248-252)