Case Report : A Case of Adult-Onset Still`s Disease Presenting with Periorbital Edema

• Published in: Journal of rheumatic diseases Vol. 20; no. 4; pp. 243 - 246
• Main Authors: Da Lim Yoon, Seohyun Lee, So Young Park, You Jae Kim, Bon San Koo, Min Wook So, Yong Gil Kim, Chang Keun Lee, Bin Yoo
• Format: Journal Article
• Language: Korean
• Published: 대한류마티스학회 30.08.2013
• Subjects: Adult-onset Still`s disease; Cellulitis; cutaneous manifestation
• ISSN: 2093-940X

Adult-onset Still`s disease (AOSD) is a systemic inflammatory disorder of unknown etiology that is characterized by high-spiking fever, arthralgia, sore throat, and skin rash. The typical rash of AOSD is an evanescent, salmon- colored erythema, which is considered to be the major diagnostic criterion. Recently, other cutaneous manifestations of AOSD, such as persistent plaque and urticaria, have been reported. Here, we report a rare case of AOSD presenting with periorbital swelling and erythema. A 47-year-old woman was presented with periorbital swelling, erythema, high fever, arthritis, and a sore throat. One year prior to admission, she was diagnosed with AOSD based on the diagnostic criteria of Yamaguchi. The patient`s periorbital swelling and erythema may not have been associated with periorbital cellulitis because they did not respond to antibiotics but did improve after treatment with steroids. Considering all of her signs and symptoms with a history of AOSD, periorbital lesion was suspected as atypical cutaneous manifestation of AOSD.