Review : Irreversible Electroporation: A Novel Image-Guided Cancer Therapy

Irreversible electroporation (IRE) is a novel tumor ablation technique using a non-thermal energy to create innumerable permanent nanopores in the cell membrane to disrupt cellular homeostasis. This disruption of cellular homeostasis initiates apoptosis which leads to permanent cell death. In our tr...

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Bibliographic Details
Published inGut and liver Vol. 4; no. s1; pp. 99 - 104
Main Authors Edward W. Lee, Susan Thai, Stephen T. Kee
Format Journal Article
LanguageKorean
Published 대한소화기내시경학회 30.09.2010
Subjects
Apoptosis
Irreversible electroporation
Tumor treatment
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Summary:Irreversible electroporation (IRE) is a novel tumor ablation technique using a non-thermal energy to create innumerable permanent nanopores in the cell membrane to disrupt cellular homeostasis. This disruption of cellular homeostasis initiates apoptosis which leads to permanent cell death. In our translational research, we have demonstrated that IRE can be a safe, fast and powerful method of tumor treatment. In this review, we present an overview of IRE ablation including a brief history of IRE, advantages and disadvantages of IRE and clinical and research implications of IRE. (Gut Liver 2010;4(Suppl. 1):
Bibliography:The Korean Society of Gastrointestinal Endoscopy
ISSN:1976-2283