폐암환자에서 급성호흡부전과 장천공을 동반한 분선충 감염증

• Published in: Tuberculosis and respiratory diseases Vol. 68; no. 1; pp. 29 - 33
• Main Authors: 김현식, Hyeon Sik Kim, 김유은, Yu Eun Kim, 윤은영, Eun Young Yun, 주지현, Ji Hyun Ju, 마정은, Jeong Eun Ma, 이기동, Gi Dong Lee, 조유지, Yu Ji Cho, 김호철, Ho Cheol Kim, 이종덕, Jong Deok Lee, 황영실, Young Sil Hwang, 정이영, Yi Yeong Jeong
• Format: Journal Article
• Language: Korean
• Published: 대한결핵 및 호흡기학회 30.01.2010
• Subjects: Immunosuppression; Intestinal Perforation; Respiratory Insufficiency; Strongyloides stercoralis
• ISSN: 1738-3536; 2005-6184

Strongyloides stercoralis is an intestinal nematode that is a parasite to humans. The infecting filariform larvae of S. stercoralis enters the host body via the bloodstream, passes through the lungs, penetrates the alveoli, and then ascends the airway to transit down the esophagus into the small bowel. The infection can persist for decades without causing major symptoms and can elicit eosinophilia of varying magnitudes. Of note, this infection can also develop into a disseminated, often fatal, disease (hyperinfection) in patients receiving immunosuppressive corticosteroids. A 65-year-old man who was receiving corticosteroid therapy for the treatment of spinal stenosis was admitted to the emergency room with complaints of abdominal pain and severe dyspnea. We detected many S. stercoralis larvae in the sputum and in the bronchoalveolar-lavage sample collected by bronchoscopy. Here, we report a fatal case of strongyloidiasis with acute respiratory failure and intestinal perforation. In addition, we provide a brief review of the relevant medical literature.