Development of Medium for Griseofulvin Production: Part 1. Screening of Medium Constituents Using the Plackett-Burman Experimental Design

The Plackett-Burman experimental design was employed to evaluate the relative importance of medium constituents of each medium for enhanced griseofulvin production by Penicillium griseofulvum MTCC 1898 and Penicillium griseofulvum MTCC 2004. It was found that the medium constituents, sucrose, K2HPO4...

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Bibliographic Details
Published inJournal of microbiology and biotechnology Vol. 12; no. 3; pp. 355 - 359
Main Authors V. Venkata Dasu, T. Panda, M. Chidambaram
Format Journal Article
LanguageKorean
Published 한국미생물생명공학회 30.06.2002
Subjects
griseofulvin
Penicillium griseofulvum
Plackett-Burman experimental design
screening
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Summary:The Plackett-Burman experimental design was employed to evaluate the relative importance of medium constituents of each medium for enhanced griseofulvin production by Penicillium griseofulvum MTCC 1898 and Penicillium griseofulvum MTCC 2004. It was found that the medium constituents, sucrose, K2HPO4, NaNO3, and FeSO4·7H2O, significantly influenced the griseofulvin production by Penicillium griseofulvum MTCC 1898. In the case of Penicillium griseofulvum MTCC 2004, lactose, glucose, and MnSO4·H2O significantly influenced the griseofulvin production.
Bibliography:The Korean Society for Applied Microbiology
ISSN:1017-7825