간에 발생한 원발성 소세포암

Primary small cell carcinoma of the liver is an extremely rare tumor. Extrapulmonary small cell carcinoma shares many features of pulmonary small cell carcinoma, including the histological appearance, the aggressive clinical behavior and the frequent short-lasting response to either chemotherapy or...

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Published inClinical and molecular hepatology Vol. 11; no. 3; pp. 289 - 292
Main Authors 유승훈, Seung Hoon Ryu, 한상영, Sang Young Han, 서성환, Sung Hwan Suh, 구영훈, Young Hun Koo, 조정환, Jeong Hwan Cho, 한승호, Seung Ho Han, 이성욱, Sung Wook Lee, 조진한, Jin Han Cho, 정진숙, Jin Sook Jeong
Format Journal Article
LanguageKorean
Published 대한간학회 22.09.2005
Subjects
Liver
Small cell carcinoma
간
소세포암
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Summary:Primary small cell carcinoma of the liver is an extremely rare tumor. Extrapulmonary small cell carcinoma shares many features of pulmonary small cell carcinoma, including the histological appearance, the aggressive clinical behavior and the frequent short-lasting response to either chemotherapy or radiotherapy. We experienced a 56-year-old man with small cell carcinoma that arose in the liver. Abdominal CT scan showed an 8 cm size, low density mass in the segment 4 of the liver and also multiple lymphadenopathies. Chest X-ray showed no abnormal finding, but the chest CT showed a right lower paratracheal lymphadenopathy. The pathological findings showed nests of small round cells with fine granular chromatin, inconspicuous nucleoli and scanty cytoplasm. Distinct and strong immunoreactions were seen for CD56 and c-kit, and sparse immunoreaction was seen for synaptophysin. Thyroid transcription factor-1 showed no immunoreaction. The tumor did not decrease in size despite chemotherapy. We report this case along with a review of the relevant literatures. (Korean J Hepatol 2005;11:289-292)
Bibliography:The Korean Association for the Study of the Liver
ISSN:2287-2728
2287-285X