IgA 신병증과 감염 후 사구체 신염이 동반된 증례

• Published in: Kidney research and clinical practice Vol. 22; no. 6; pp. 773 - 776
• Main Authors: 이정록, Lee Jeong Log, 신영신, Sin Yeong Sin, 이승우, Lee Seung U, 최현철, Choe Hyeon Cheol, 김형욱, Kim Hyeong Ug, 박철휘, Park Cheol Hwi, 최영진, Choe Yeong Jin, 장윤식, Jang Yun Sig, 방병기, Bang Byeong Gi
• Format: Journal Article
• Language: Korean
• Published: 대한신장학회 30.11.2003
• Subjects: Coexistence; Ig A nephropathy; Postinfectious glomerulonephritis
• ISSN: 2211-9132

A 33-year-old man was admitted with macroscopic hematuria and systemic edema appearing after an acute upper respiratory tract infection. On admission, hypertension, nephrotic syndrome were evident together with a decreased renal function. Renal biopsy showed markedly increased mesangial cells acompanied with increase of endocapillary cells including neutrophils. Immunofluorescence microscopy showed granular deposits of C3 and IgA. Electron Microscopy revealed so-called "hump" on the subepithelial area. These features were consistent with the coexistence of IgA nephropathy (IgAN) and post-infections glomerulonephritis. It is not clear about the prognosis and the therapeutic regimen in the patient who develop above situation. Although the patient showed still persistent proteinuria, high dose steroid therapy was probably useful for improving the disease. (Korean J Nephrol 2003;22(6):773-776)