증레 : 식도의 melanosis 에서 악성변화한 원발성 악성 흑색종 1 예

• Published in: The Korean journal of medicine Vol. 61; no. 1; pp. 71 - 76
• Main Authors: 이학준, Hak Jun Lee, 최선택, Sun Taek Choi, 은종렬, Jong Ryul Eun, 권순욱, Soon Uk Kwon, 김봉준, Bong Jun Kim, 최교원, Kyo Won Choi, 송영두, Young Doo Song, 장병익, Byeong Ik Jang, 김태년, Tae Nyun Kim, 정문관, Moon Kuxm Chung
• Format: Journal Article
• Language: Korean
• Published: 대한내과학회 01.07.2001
• ISSN: 1738-9364

Primary malignant melanoma of the esophagus (PMME) is an extremely rare but aggressive disease that composes less than 0.1% of all primary malignant neoplasm of the esophagus. PMME was first reported in 1906 and nearly 180 cases of primary esophageal malignant melanoma have been published in the medical literature. Symptoms of the primary malignant melanoma of the esophagus mimic that of any malignant obstructing lesion of the esophagus and the metastatic spread by lymphatics and vascular routes are common. Resection of the tumor with an anastomotic procedure seems to be the treatment of choice, however prognosis is poor. At present, chemotherapy and immunotherapy have no major role in treatment. We report a case of 67-year-old man with primary malignant melanoma of the esophagus originated from esophageal melanosis with a review of the literature. (Korean J Med 61:71-76, 2001)