심한 저인혈증을 동반한 입원 환자의 임상적 고찰

• Published in: Kidney research and clinical practice Vol. 10; no. 3; pp. 330 - 335
• Main Authors: 강신주, 김지윤, 한덕희, 박현진, 유병희, 문성수
• Format: Journal Article
• Language: Korean
• Published: 대한신장학회 01.01.1991
• ISSN: 2211-9132

Hypophosphatemia is a relatively common findings in hospitalized patients, especially severe hypophos- phatemia has been associated with significant morbid- ity. We reviewed severe hypophosphatemic patients who admitted in National Medical Center between January, 1989 and December, 1989. The following results were obtained. 1) The incidence of hypophosphatemia was 9.6%(364 of 2762) and 44 patients (3.3%) showed severe hypo- phosphatemia. 2) Contributing causes were intravenous glucose administration, antacids treatment, diarrhea and fasting in order of frequency. 3) Other electrolytes abnormalities were hypocal- cemia (54.5%), hypomagnesemia (57.2%), hyponatremia (31.8%) and hypokalemia (27.3 %). 4) Fifteen patients (34.1%) with severe hypophos- phatemia showed abnormal renal function. 5) The odds ratio for developing the severe hypophos- phatemia was 43.1 (95% confidence interval 2.9 to 623.6) in patients with diabetic ketoacidosis, 30.1 (10.8 to 83.8) in septic patients, 9.9 (1.2 to 82.6) in alcoholics, and 9.2 (l. 1 to 75.7 ) in malnourished patients. 6) Overall mortality of patients with severe hypo- phosphatemia was 27.3% (12 of 44). From the above results, we conclude that severe hypophosphatemia is a relatively common finding in hospitalized patients, especially in those with certain medieal conditions (diabetic ketoacidosis, septicema, aicoholics & malutrition). It is associated with signifi- cant excess morbidity