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Thymic carcinoma is a relatively rare neoplasm of thymus and about 150 cases have been reported until now. It is a thymic epithelial neoplasm with obvious cytologic atypia and usually located in the anterior and superior mediastinum. It has several histologic types-well-differentiated (keratinizing)...

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Published inThe Korean journal of medicine Vol. 54; no. 2; pp. 278 - 284
Main Authors 강양호, Yang Ho Kang, 전두수, Doo Soo Jeon, 이효진, Hyo Jin Lee, 박성민, Sung Min Park, 이준홍, Jun Hong Lee, 오현명, Hyun Myung Oh, 김윤성, Yun Seong Kim, 김병진, Byung Jin Kim, 이민기, Min Ki Lee, 박순규, Soon Kew Park
Format Journal Article
LanguageKorean
Published 대한내과학회 01.02.1998
Subjects
Mediastinum
Squamous Cell Carcinoma
Thymic Carcinoma
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Summary:Thymic carcinoma is a relatively rare neoplasm of thymus and about 150 cases have been reported until now. It is a thymic epithelial neoplasm with obvious cytologic atypia and usually located in the anterior and superior mediastinum. It has several histologic types-well-differentiated (keratinizing) squamous cell carcinoma and pooly-differentiated (nonkeratinizing) squamous cell carcinoma, small cell carcinoma, clear cell carcinoma and adenosquamous cell carcinoma. The symtoms of thymic carcinoma is anterior chest pain, dyspnea, coughing and SVC syndrome usually caused by compression of mediastinal organs. Histologic grade is the most important prognostic factor. The prognosis of well-differentiab4 (keratinizing) squamous cell carcinoma subtype is better than other subtypes. But all of the variants of thymic carcinoma are highly lethal and should be treated aggressively with all modalities of therapy. Authors report three cases of thymic carcinoma diagnosc4 by clinical, radiographic, and histologic findings with review of the literature.
Bibliography:The Korean Association Of Internal Medicine
ISSN:1738-9364