고립성 식도 흑피증 1 예

• Published in: The Korean journal of medicine Vol. 49; no. 6; pp. 865 - 870
• Main Authors: 라성찬, Seong Chan La, 전동하, Dong Ha Chun, 어중건, Jung Gun Uh, 김계혁, Gyeu Hyuk Kim, 정준, Jun Jeong, 변흥열, Heung Yeal Byun, 이승은, Seung Eun Lee, 조주영, Joo Young Cho, 박영희, Young Hee Park, 박찬욱, Chan Uk Park, 이문성, Moon Sung Lee, 심찬섭, Chan Sup Shim
• Format: Journal Article
• Language: Korean
• Published: 대한내과학회 01.12.1995
• Subjects: Endoscopic esophageal mucosal resection EEMR; Esophageal malignant melanoma; Esophageal melanosis
• ISSN: 1738-9364

Esophageal melanosis is discrete proliferation of melanocytes in the basal layer of the esophageal epithelium. Histologically, pigmented melanocytes lacking atypia and mitoses are observed amongst the keratinocytes in the basal layer of the esophageal mucosa. Junctional activity is absent. Esophageal melanosis has been reported synchronously with or preceding malignant melanoma and the possibility that it might be a premalignant lesion has been suggested, The value of sampling these pigmented lesions during endoscopy is emphasized as a means of obtaining well preserved material for the evaluation of a lesion which some authorities have viewed as a possible precusor for esophageal malignant melanoma. The management of esophageal melanosis consists of complete destruction of any isolated melanotic pigmentation by surgical operation, endoscopic electrocoagulation or laser. We experienced a case of isolated esophageal melanosis associated with benign gastric ulcer in a 63-year old man, who was admitted to our hospital complaining of hematemesis. Endoscopic esophageal mucosal resection (EEMR) was performed for the management of isolated esophageal melanosis