Case Reports : Successful Treatment with Ganciclovir for Cytomegalovirus Duodenitis following Allogenic Bone Marrow Transplantation

Cytomegalovirus(CMV) disease is a major cause of morbidity and mortality in immunocompromised patients. CMV enteritis should be considered when nausea and vomiting continue 3 to 4 weeks after bone marrow transplantation(BMT). The treatment of CMV enteritis is not well established. We report a CMV du...

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Published inThe Korean journal of internal medicine Vol. 14; no. 1; pp. 91 - 94
Main Authors Jin Hee Ahn, Je Hwan Lee, Kyoo Hyung Lee, Woo Kun Kim, Jung Shin Lee, Hye Seung Bahng, Hwoon Yong Jung, Yang Soo Kim, On Ja Kim, Sang Hee Kim
Format Journal Article
LanguageKorean
Published 대한내과학회 25.01.1999
Subjects
BMT
Cytomegalovirus ( CMV )
Ganciclovir
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Summary:Cytomegalovirus(CMV) disease is a major cause of morbidity and mortality in immunocompromised patients. CMV enteritis should be considered when nausea and vomiting continue 3 to 4 weeks after bone marrow transplantation(BMT). The treatment of CMV enteritis is not well established. We report a CMV duodenitis patient following allogenic bone marrow transplantation. The patient had prolonged nausea and vomiting for 5 weeks after bone marrow transplantation and CMV duodenitis was diagnosed by the gastroduodenoscopic mucosal biopsy which showed cytomegalic cells. Ganciclovir treatment for 3 weeks resulted in the resolution of symptoms and promoted healing of the lesion. The patient was free of CMV infection until 288 days after allogenic BMT without maintenance ganciclovir treatment.
Bibliography:The Korean Association Of Internal Medicine
ISSN:1226-3303
2005-6648