제왕절개술을 위한 지주막하 고비중 0.25 % Bupivacaine - Morphine 에 대한 Fentanyl 첨가의 효과

• Published in: Korean journal of anesthesiology Vol. 27; no. 12; pp. 1779 - 1785
• Main Authors: 윤석화, Seok Hwa Yoon, 김혜자, Hae Ja Kim, 손수창, Soo Chang Son, 신용섭, Yong Sup Shin, 최세진, Se Jin Choi
• Format: Journal Article
• Language: Korean
• Published: 대한마취통증의학회(구 대한마취과학회) 30.12.1994
• Subjects: Bupivacaine; Fentanyl; Morphine; Spinal Anesthesie
• ISSN: 2005-6419; 2005-7563

To investigate the effect of intrathecal fentanyl,36 ASA physieal status 1 or 2 parturients who underwent cesarean section with apinal anesthesis using 0.25% bupivacaine in 5.0% dextroae with 0.25mg morphine were studied. Patients were randomly allocated to receive either saline 0.2ml (group 1, n=17) or fentanyl 10μg(group 2, n=19) in 3.525ml volume mixed with the bupivacaine with morphine. Spinal anesthesia was performed in sitting position using a 25 guage spinal needle. At the completion of injection, patients immediately turned supine with left uterine diaplacement. There was no statistically significant difference in the incidence of the hypotension between groups. The progress of sensory and motor blocks was similar in the two groups. The times from drug injection ta the onset to maximal sensory blockade and complete motor blockade, complete recovery of sensation and motor power were not different between groups. post delivery,the incidence of visceral pain were significantly less in group 2, as 2 of 19 patients(10%) in group 2 compared to 8 of 17 patients(47%) in group 1(p< 0.05). The effective analgesia time was no significant different: 31.7±2.5 hour in group 1 compared to 28.6±5.6 hour in Group 2. The ineidence of patients not requiring narcotics until discharge was similar in two groups. No patient showed any evidence of respiratory depression. The incidence of other side effects,such as nausea,vomiting and pruritus was not different between groups. No neonate had an Apgar score below 7.