악성 흑색극세포증을 동반한 진행성 위암

• Published in: The Korean journal of gastroenterology Vol. 34; no. 5; pp. 682 - 687
• Main Authors: 전은정, Eun Jung Jun, 채은영, Eun Young Chae, 이성원, Seong Won Lee, 채현석, Hiun Suk Chae, 한석원, Sok Won Han, 최규용, Kyu Yong Choi, 정인식, In Sik Chung, 차상복, Sang Bok Cha, 박두호, Doo Ho Park
• Format: Journal Article
• Language: Korean
• Published: 대한소화기학회 01.01.1999
• Subjects: Malignant acanthosis nigricans; Stomach cancer
• ISSN: 1598-9992

Acanthosis nigricans is a mucocutaneous eruption that occurs in a strikingly exuberant form as a marker for a highly malignant and rapidly fatal internal cancer. A case of poorly-differentiated adenocarcinoma (Borrmann type 3) observed in the stomach of a 24-year-old man was associated with the typical skin manifestations of acanthosis nigricans. The advanced tumor in antrum to high body was unresectable due to extensive metastasis. The cutaneous lesions were characterized by hyperpigmentation and papillary hypertrophy at both axilla and inguinal areas without oral mucosal involvement. In spite of the systemic chemotherapy, there was no response about the tumor burden and the cutaneous lesions. Three months after diagnosis, he died of continuous blood oozing from the tumor mass, hepatic failure and malnutrition. (Kor J Gastroenterol 1999;34:682 - 687)