수소호기검사와 소장통과 신티그라피의 구강 , 맹장 통과시간 비교

• Published in: The Korean journal of gastroenterology Vol. 30; no. 5; pp. 565 - 573
• Main Authors: 문정섭, Jeong Seop Moon, 송치욱, Chi Wook song, 최재걸, Jae Gol Choe, 현진해, Jin Hae Hyun
• Format: Journal Article
• Language: Korean
• Published: 대한소화기학회 01.01.1998
• Subjects: Oro-cecal transit time Hydrogen breath test Radionuclide scintigraphy
• ISSN: 1598-9992

Background/Aims: Patients with gastrointestinal symptoms, and motility disorclers are considered a main part of disease entities. Various motility tests have been used but the motility of the small bowel is hard to evaluate directly. Measurement of oro-cecal transit time u:;ing the hydrogen breath test has been used for the evaluation of small bowel motility, but critericn to indicate cecal arrival was different arnong many studies. We aimed to identify the criterion of cecal amval in hydrogen breath test compared with radionuclide scintigraphy. Methods: Subjects were 30 volunteers with no gastrointestinal symptom and no past history of diarrhea, enema, or antibiotic intake for three weeks before the study. We performed hydrogen breath tests and enteric radionuclide scintigraphy simultaneously every fifteen minutes for six hours after the intake of the test meal composed of an egg sandwich with 1mCi 99mTc sulfur colloid:md lactulose. We compared the results of oro-cecal transit time by scintigraphy with the hydro,;en breath test, in which cecal arrival was defined by various criteria of H2 concentration incri:ment above basal level(eg. 3, 5, 10 ppm and double of baseline). Results: Oro-cecal transit time by scintigraphy was 87.5+-20.1 minutes in healthy volunteers and their positive rate of breath hyd-ogen was 80% in criterion of 10ppm, 66.6% in criterion of 20pprn. Oro-cecal transit time by the hydrogen breath test in which each criterion was defined by 3, 5, 10 ppm and double increase above baseline was 91.8+-24.6, 106.9+-32.2, 117.9+-37.7 and 92.4+-30.2 minutes respectively. R<:lationship of oro- cecal transit time by scintigraphy and hydrogen breath test was greatest in criterion of 3ppm increase above basal level in the hydrogen breath test. Conclusions: Oro-cecal transit time by the hydrogen breath test was convenient and was also a non-invasive method to evaluate small bowel motility and the most accurate criterion to show cecal arrival was 3ppm increase above baseline compared with the results of radionuclide scintigraphy. (Korean J Gastro.nterol 1997; 30: 565-573)