Prosthetic valve endocarditis caused by Propionibacterium species successfully treated with coadministered rifampin: report of two cases

We describe two cases of prosthetic valve endocarditis caused by Propionibacterium spp. successfully treated with a combination of rifampin and intravenous penicillin. Rifampin was chosen due to its promising activity against planktonic and biofilm Propionibacterium, its favourable minimal inhibitor...

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Bibliographic Details
Published inBMJ Case Reports Vol. 2013
Main Authors Braun, Dominique Laurent, Hasse, Barbara Katharina, Stricker, Julia, Fehr, Jan Sven
Format Report
LanguageEnglish
Published BMJ Publishing Group Ltd 2013
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Summary:We describe two cases of prosthetic valve endocarditis caused by Propionibacterium spp. successfully treated with a combination of rifampin and intravenous penicillin. Rifampin was chosen due to its promising activity against planktonic and biofilm Propionibacterium, its favourable minimal inhibitory concentrations, its excellent oral bioavailability and tissue penetration.
Bibliography:istex:7226636E7E228D24F4C63F5DC6E77D92176C7E57
href:casereports-2013-bcr-2012-007204.pdf
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ArticleID:bcr-2012-007204
ISSN:1757-790X
DOI:10.1136/bcr-2012-007204