Large retroperitoneal low-grade extraskeletal osteosarcoma

Low-grade extraskeletal osteosarcoma is an extremely rare neoplasm with only nine cases reported in the literature, in which only one case involved the retroperitoneum. Tendency to dedifferentiate as well as recur with high-grade variant is known and management principles are not well defined, neces...

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Bibliographic Details
Published inBMJ Case Reports Vol. 2014
Main Authors Jaipuria, Jiten, Kumar, Ashok, Rao, Adla Satyanarayan, Kataria, Satya Pal
Format Report
LanguageEnglish
Published BMJ Publishing Group Ltd 21.03.2014
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Summary:Low-grade extraskeletal osteosarcoma is an extremely rare neoplasm with only nine cases reported in the literature, in which only one case involved the retroperitoneum. Tendency to dedifferentiate as well as recur with high-grade variant is known and management principles are not well defined, necessitating a continuous review of literature. We report management of the largest such retroperitoneal tumour (18.0 cm× 18.3 cm×17.8 cm) in a 38-year-old man, which was treated with surgery followed by six cycles of cisplatin (90 mg/m2 days 1 and 2) and doxorubicin (75 mg/m2 day 3), cycled every 3 weeks (with granulocyte colony stimulating factor support as necessary). The patient is disease free after 3 years of follow-up.
Bibliography:local:casereports;2014/mar21_1/bcr-2014-203745
href:casereports-2014-bcr-2014-203745.pdf
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ArticleID:bcr-2014-203745
istex:801B6E38D9E92DDDEBBE5A0E54E3E0A12AB0BBDF
ISSN:1757-790X
DOI:10.1136/bcr-2014-203745