Bioactive Compounds As Potential Remedy Against Coronaviruses

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), a positive-stranded RNA virus reported in late 2019, sparked the current coronavirus illness known as the COVID-19 pandemic which has aroused worldwide health concerns. Many chemical compounds having antiviral activity are currently being...

Full description

Saved in:
Bibliographic Details
Published inMicrobial Products Vol. 1; pp. 417 - 432
Main Authors Kuntal, Kaur, Prabhleen, Dawer, Sakshi, Yashpal, Madhu, Kalra, Seema, Chaudhary, Archna
Format Book Chapter
LanguageEnglish
Published CRC Press 2023
Edition1
Subjects
Viral Replication
TLR Signaling
Dose Dependent Blockage
Saikosaponin B
Enter Host Cells
CoV Infection
Plpro
Spike Protein
NSPs
Nucleoside Analog
Bioactive compounds
RdRp
Mediates Membrane Fusion
Artepillin C
3Clpro
Ace Inhibitor Peptide
Main Protease
RNA - Bind Domain
RNA Dependent RNA Polymerase
Nucleocapsid Protein
Viral RNA
Anti-corona viral drugs
Viral Target Protein
Marine Sponges
S glycoprotein
TCM Formula
Coronavirus
S2 Subunit
Diagnostic Test Development
SARS CoV
MERS
Online AccessGet full text

Cover

More Information
Summary:Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), a positive-stranded RNA virus reported in late 2019, sparked the current coronavirus illness known as the COVID-19 pandemic which has aroused worldwide health concerns. Many chemical compounds having antiviral activity are currently being investigated to find probable therapies for SARS-CoV-2-infected patients. Various bioactive compounds which are already being used to cure several diseases have been documented to possess antiviral properties. These may serve as potential drug candidates against SARS-CoV-2. Such compounds are derived from diverse biological sources like algae, marine sponges and herbal medicinal plants, and others have been identified to have potential to treat COVID infection by either acting as nucleotide analogs, by targeting various viral components like S glycoprotein, 3CLpro and Plpro, RdRp, or by employing other specified mechanisms against viral replication. In this chapter, we aim to document potential bioactive compounds that have been identified to act as likely anti-corona viral drugs. We believe this chapter will act as a comprehensive resource containing information on all bioactive compounds that can inhibit viral replication and hence act as a crucial solution to combat the pandemic.
ISBN:9781032308395
1032308206
9781032308203
1032308397
DOI:10.1201/9781003306931-28