Fetal-maternal interface: A chronicle of allogeneic coexistence

The existence of allogeneic cells within an individual has been demonstrated in multiple fields such as hematopoietic stem cell or solid organ transplantation, non-depleted blood transfusions and the most common form which is bidirectional maternal-fetal cell trafficking, whereby cells from the fetu...

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Bibliographic Details
Published inChimerism Vol. 3; no. 1; pp. 18 - 23
Main Authors Pujal, Josep-Maria, Roura, Santiago, Muñoz-Marmol, Ana M., Mate, Jose-Luis, Bayes-Genis, Antoni
Format Report
LanguageEnglish
Published Taylor & Francis 01.01.2012
Subjects
fetal-maternal interface
fish
microchimerism
placenta
tolerance
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Summary:The existence of allogeneic cells within an individual has been demonstrated in multiple fields such as hematopoietic stem cell or solid organ transplantation, non-depleted blood transfusions and the most common form which is bidirectional maternal-fetal cell trafficking, whereby cells from the fetus pass through the placental barrier. In order to graphically illustrate this early natural phenomenon that initiates the journey of a child's cells within the mother's blood and other tissues, we used a new procedure in microscopy imaging generating Large Scale Panoramic Pictures (LSPP). This technique can also be extended to explore a broad diversity of experimental models.
ISSN:1938-1956
1938-1964
DOI:10.4161/chim.19439