Antiphospholipid Syndrome following Toxoplasma Retinochoroiditis

Purpose: To report a case of antiphospholipid syndrome (APS) following toxoplasma retinochoroiditis. Design: Interventional case report. Method: The patient was a 24-year-old female with an attack of visual loss due to toxoplasma retinochoroiditis concomitant with branch retinal vein occlusion. Reti...

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Bibliographic Details
Published inOcular Immunology and Inflammation Vol. 19; no. 5; pp. 311 - 313
Main Authors Tavakoli, Mehdi, Roghaee, Shiva, Soheilian, Roham, Soheilian, Masoud
Format Report
LanguageEnglish
Published Taylor & Francis 01.10.2011
Subjects
Antiphospholipid Syndrome
Branched Retinal vein occlusion (BRVO)
ocular toxoplosmosis
Retinochoroiditis
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Summary:Purpose: To report a case of antiphospholipid syndrome (APS) following toxoplasma retinochoroiditis. Design: Interventional case report. Method: The patient was a 24-year-old female with an attack of visual loss due to toxoplasma retinochoroiditis concomitant with branch retinal vein occlusion. Retinitis resolved with anti-toxoplasma treatment. However, a recurrent episode of BRVO and vitreous hemorrhage occurred later. Result: In systemic evaluation, evidence of APS was detected, including high titers of anti-cardiolipin antibody, increased beta-2 microglobulin and anti-toxoplasma IgG antibody, and also low titers of C3, C4, and CH50. Conclusion: Ocular toxoplasmosis should be included in the list of etiologies of secondary APS. Systemic evaluation for detection of APS is a necessary approach to patients with toxoplasma retinochoroiditis and concomitant vascular accident.
ISSN:0927-3948
1744-5078
DOI:10.3109/09273948.2011.596302