Severe hypercalcaemia and acute renal failure in an infant with subcutaneous fat necrosis

Subcutaneous fat necrosis (SFN) in the newborn is a form of panniculitis which presents with erythematous nodules and indurated plaques. Severe life-threatening hypercalcaemia can occur as a late complication. A 2-month-old girl presented with severe hypercalcaemia and acute renal injury as a compli...

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Published inPaediatrics and International Child Health Vol. 41; no. 3; pp. 221 - 225
Main Authors İnce Becerir, Tülay, Altincik, Ayça, Özhan, Bayram, Yüksel, Selçuk
Format Report
LanguageEnglish
Published Taylor & Francis 03.07.2021
Subjects
Acute renal failure
hypercalcaemia
pamidronate
subcutaneous fat necrosis
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Summary:Subcutaneous fat necrosis (SFN) in the newborn is a form of panniculitis which presents with erythematous nodules and indurated plaques. Severe life-threatening hypercalcaemia can occur as a late complication. A 2-month-old girl presented with severe hypercalcaemia and acute renal injury as a complication of SFN. She was admitted to hospital with the chief complaint of failure to thrive. She had a history of therapeutic hypothermia. After successful treatment of the hypercalcaemia with bisphosphonates, the acute renal injury recovered spontaneously. In neonates with SFN, acute renal injury is a rare complication of hypercalcaemia. Timely prevention of the complications of hypercalcaemia in SFN is essential.
ISSN:2046-9047
2046-9055
DOI:10.1080/20469047.2021.1883960