Agrammatic primary progressive aphasia in two dextral patients with right hemispheric involvement

Agrammatic primary progressive aphasia (PPA-G) has been known to be associated with focal brain atrophy involving the left posterior frontal and anterior insular regions. However, aphasia can also rarely result from right hemispheric lesions in right-handed patients, so-called crossed aphasia in dex...

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Published inNeurocase Vol. 20; no. 1; pp. 46 - 52
Main Authors Jeong, Eun Hye, Lee, Yong Joo, Kwon, Miseon, Kim, Jae Seung, Na, Duk L., Lee, Jae-Hong
Format Report
LanguageEnglish
Published Routledge 02.01.2014
Subjects
Agrammatism
Crossed aphasia
Magnetic resonance imaging
Positron emission tomography
Primary progressive aphasia
Progressive nonfluent aphasia
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Summary:Agrammatic primary progressive aphasia (PPA-G) has been known to be associated with focal brain atrophy involving the left posterior frontal and anterior insular regions. However, aphasia can also rarely result from right hemispheric lesions in right-handed patients, so-called crossed aphasia in dextrals (CAD). We report two right-handed patients with PPA-G whose 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) showed hypometabolism predominantly in the right hemisphere, implicating "crossed PPA-G."
ISSN:1355-4794
1465-3656
DOI:10.1080/13554794.2012.732084