Deterioration of CD4 T-cells in HIV/AIDS individuals infected with pathogenic Microsporidium in Benue state, Nigeria

• Published in: Bio-science research bulletin Vol. 29; no. 2; pp. 57 - 64
• Main Authors: Yako, JB, Yako, AB, Ajayi, JA, Makpo, JK, Auta, KI, Banyigyi, HA, Ojo, SM
• Format: Journal Article
• Language: English
• Published: BPAS Research 01.07.2013
• Subjects: Acquired immune deficiency syndrome (AIDS); HIV/AIDS individuals; Strain of pathogenic microsporidium
• ISSN: 0970-0889; 2320-3161

Preliminary survey in Benue State shows that 96 HIV/AIDS individuals were infected with pathogenic microsporidium. 966, 42 (4.3%) males CD4 T-cells count were <335 cell/μl, and in the female category 1042, 54 (5.2%) CD4 T-cells were <320 cell/μl at the first CD4 count. The strain of pathogenic microsporidium in HIV/AIDS individuals was observed as a leading cause of diarrhea, and a fall in the CD4 T-cells count after 90 days of re-evaluation. Among the age group of 30–39 years, the CD4 cells count gradually deteriorate to <200 cell/μl indicating high risk to acquired immune deficiency syndrome (AIDS) and opportunistic infections. However, there was a significant relationship among sexes given that, Z=1.039<±1.96 in other words, microsporidium was solely depended on age which shows no significant relationship among the age groups (x2=7.815>0.05).