Recent advances of in vivo magnetic resonance imaging with laser-polarized noble gases

The field of polarization-based magnetic resonance imaging has expanded rapidly in the past few years. Realization of this new modality of medical imaging is dependent upon the production of large quantities of noble gas. Additionally the noble gas must be delivered to the subject in controlled and...

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Bibliographic Details
Published in1997 IEEE Nuclear Science Symposium Conference Record Vol. 2; pp. 1337 - 1339 vol.2
Main Authors Welsh, R.C., Chupp, T.E., Coulter, K.P., Rosen, M.S., Swanson, S.D.
Format Conference Proceeding
LanguageEnglish
Published IEEE 1997
Subjects
Biomedical imaging
Diode lasers
In vivo
Magnetic flux
Magnetic resonance imaging
Medical control systems
Optical arrays
Polarization
Production
Semiconductor laser arrays
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ISBN0780342585
9780780342583
ISSN1082-3654
DOI10.1109/NSSMIC.1997.670568

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Summary:The field of polarization-based magnetic resonance imaging has expanded rapidly in the past few years. Realization of this new modality of medical imaging is dependent upon the production of large quantities of noble gas. Additionally the noble gas must be delivered to the subject in controlled and efficient manner. The process of delivery must also preserve a large fraction of the polarization for the method to be effective. The authors have constructed a polarization and delivery system that is currently in use in the fringe field of a MRI magnet. This polarization system utilizes high power laser diode arrays as a practical means to delivery a high flux of polarized photons. The authors have done initial imaging studies using laser polarized xenon-129. The discussion covers the technique and optimization of the polarized noble gas production and delivery. The efficacy of the system is demonstrated in the spectroscopic and spatially resolved NMR data.
ISBN:0780342585
9780780342583
ISSN:1082-3654
DOI:10.1109/NSSMIC.1997.670568