Ventricularwall thickness analysis in acute myocardial infarction and hypertrophic cardiomyopathy

Ventricular wall thickness and thickening are important biomarkers that are informative about myocardial function, especially for patients suffering from acute myocardial infarction (AMI) and hypertrophic cardiomyopathy (HCM). In this paper, the medial modeling is applied to produce thickness and th...

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Published in2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro pp. 670 - 673
Main Authors Hui Sun, Tobon-Gomez, C., Das, S.R., Huguet, M., Yushkevich, P.A., Frangi, A.F.
Format Conference Proceeding
LanguageEnglish
Published IEEE 01.06.2009
Subjects
Acute Myocardial Infarction
Ambient intelligence
Biomedical computing
Cardiology
Heart
Heart wall thickness
Hypertrophic Cardiomyopathy
Image segmentation
Myocardium
Shape
Shape Analysis
Skeleton
Statistical analysis
Systolic thickening
Thickness measurement
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ISBN1424439310
9781424439317
ISSN1945-7928
DOI10.1109/ISBI.2009.5193136

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Summary:Ventricular wall thickness and thickening are important biomarkers that are informative about myocardial function, especially for patients suffering from acute myocardial infarction (AMI) and hypertrophic cardiomyopathy (HCM). In this paper, the medial modeling is applied to produce thickness and thickening maps on skeleton meshes, on which surface-based statistical analysis can be directly performed. As an example, the statistics derived from healthy group is used to identify regions with abnormal thickness or thickening in a new patient. Cluster-based analysis is also performed to study the prevalent patterns of thickness and thickening change for AMI and HCM patients in the dataset.
ISBN:1424439310
9781424439317
ISSN:1945-7928
DOI:10.1109/ISBI.2009.5193136