Higuchi fractal dimension and spectral entropy as measures of depth of sedation in intensive care unit

The ability of two easy-to-calculate nonlinear parameters, the Higuchi fractal dimension (HDf) and spectral entropy, to follow the depth of sedation in the intensive care unit is assessed. For comparison, the relative beta ratio is calculated. The results are evaluated using clinical assessment of t...

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Bibliographic Details
Published inThe 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society Vol. 1; pp. 526 - 529
Main Authors Anier, A., Lipping, T., Melto, S., Hovilehto, S.
Format Conference Proceeding
LanguageEnglish
Published IEEE 2004
Subjects
Anesthesia
beta ratio
Cutoff frequency
depth of sedation
Drugs
Electroencephalography
Entropy
Fractals
High definition video
Higuchi fractal dimension
Signal analysis
spectral entropy
State estimation
Surgery
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Summary:The ability of two easy-to-calculate nonlinear parameters, the Higuchi fractal dimension (HDf) and spectral entropy, to follow the depth of sedation in the intensive care unit is assessed. For comparison, the relative beta ratio is calculated. The results are evaluated using clinical assessment of the Ramsay score. The results show that the HD/sub f/ discriminates well between Ramsay scores 2-4 while beta ratio is superior for deeper levels of sedation. The value of the HD/sub f/ correlates highly with the cutoff frequency of the low-pass prefilter while spectral entropy is sensitive to the length of the analysis window.
ISBN:0780384393
9780780384392
DOI:10.1109/IEMBS.2004.1403210