Ultra sensitive and compact VCSEL-based biosensor for detection of protein interactions and dengue antibodies

We report a label-free biosensor system that consists of a tunable VCSEL, a plastic guided mode resonant filter and two pin detectors. The biosensor has'demonstrated the sensitivity of detecting antigen proteins concentration as low as Ipg/ml (6.7fM) and antibodies to dengue virus.

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Bibliographic Details
Published inDigest of the LEOS Summer Topical Meetings Biophotonics/Optical Interconnects and VLSI Photonics/WBM Microcavities, 2004 p. 2 pp.
Main Authors Mateus, C.F.R., Huang, M.C.Y., Parekh, D., Chang-Hasnain, C.J., Foley, J.E., Lim, W., Beatty, P.R., Li, P., Cunningham, B.T.
Format Conference Proceeding
LanguageEnglish
Published IEEE 2004
Subjects
Biosensors
Mice
Optical filters
Optical surface waves
Proteins
Resonance
Time measurement
Tunable circuits and devices
Vertical cavity surface emitting lasers
Wavelength measurement
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Summary:We report a label-free biosensor system that consists of a tunable VCSEL, a plastic guided mode resonant filter and two pin detectors. The biosensor has'demonstrated the sensitivity of detecting antigen proteins concentration as low as Ipg/ml (6.7fM) and antibodies to dengue virus.
ISBN:0780383060
9780780383067
ISSN:1099-4742
2376-8614
DOI:10.1109/LEOSST.2004.1338664