Biyobelirteçler, koroner arter hastalığının şiddetini gösterebilir mi?
Purpose: Biomarkers are useful measures assisting the diagnosis, treatment, and prognosis of cardiovascular diseases. They can predict the severity of cardiovascular diseases, especially in acute myocardial infarction at the emergency department. We aimed to investigate the severity of cardiovascula...
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Published in | Cukurova Medical Journal Vol. 46; no. 3; pp. 883 - 888 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | Turkish |
Published |
Çukurova Üniversitesi Tıp Fakültesi
01.03.2021
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Subjects | |
Online Access | Get full text |
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Summary: | Purpose: Biomarkers are useful measures assisting the
diagnosis, treatment, and prognosis of cardiovascular
diseases. They can predict the severity of cardiovascular
diseases, especially in acute myocardial infarction at the
emergency department. We aimed to investigate the
severity of cardiovascular disease using three biomarkers,
namely cardiac troponins, C-reactive protein (CRP), and
procalcitonin in patients with ST-elevation myocardial
infarction who presented to the emergency department.
Material and Methods: The study included a total of 166
patients that presented with ST-elevation myocardial
infarction (STEMI) in the first three hours of symptom
onset and underwent coronary angiography. SYNTAX
(SS) scores were calculated, and based on these scores, two
groups were formed. High-sensitivity troponin T (Hs-
TnT), high-sensitivite CRP (Hs-CRP), and procalcitonin
levels were measured at the presentation.
Results: Although the high sensitive troponin, Hs-CRP
values were higher in the SYNTAX score>20 groups,
there was no statistically significant difference between the
two groups. There was no significant difference in the PCT
measurements between the two groups
Conclusion: When Hs-TnT and Hs-CRP are evaluated
together in patients with STEMI with a high SS, it may be
predictive in early determining the severity of coronary
artery disease. |
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ISSN: | 2602-3032 2602-3040 |
DOI: | 10.17826/cumj.865009 |