Long-Term Prognostic Value of Mean Platelet Volume in Patients with Hypertension

Background: Although it has been shown that high mean platelet volume (MPV) is associated with target organ damage in hypertensive patients, the relationship between MPV and the development of long-term major adverse cardiovascular events (MACE) has not been thoroughly investigated. In this study, w...

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Bibliographic Details
Published inActa Cardiologica Sinica Vol. 37; no. 5; pp. 504 - 511
Main Authors Hamdi Pusuroglu, Ahmet Ya ar Cizgici, Ali R za Demir, Begum Uygur, Ender Ozal
Format Journal Article
LanguageChinese
Published 台灣 中華民國心臟學會 01.09.2021
Subjects
Cardiovascular event
Hypertension
Long-term
Mean platelet volume
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SCIE
Scopus
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Summary:Background: Although it has been shown that high mean platelet volume (MPV) is associated with target organ damage in hypertensive patients, the relationship between MPV and the development of long-term major adverse cardiovascular events (MACE) has not been thoroughly investigated. In this study, we investigated the relationship between MPV and long-term MACE in hypertensive patients. Methods: From September 2011 to July 2017, 1507 patients with hypertension were included in this study. Ambulatory blood pressure monitoring was performed in all patients. Patients with chronic renal failure, cardiovascular disease, chronic systemic disease and white coat hypertension were excluded from the study. MACE were defined as myocardial infarction, stroke and cardiovascular mortality. Patients were followed-up until january 2020. Results: The mean follow-up duration was 87 (83.3 24.4) months, and 876 patients completed the study. MACE developed in 79 patients, while 797 patients were event-free. In univariate Cox reg
ISSN:1011-6842