Systemic Inflammatory Response Syndrome is an Independent Predictor of One-Year Mortality in Patients with Acute Myocardial Infarction

Background: Convincing evidence suggests that inflammatory biomarkers are associated with an increased risk among patients with acute myocardial infarction (AMI). However, the impact of systemic inflammatory response (SIRS) on one-year clinical outcomes remains uncertain. Herein we investigated the...

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Published inActa Cardiologica Sinica Vol. 33; no. 5; pp. 477 - 485
Main Authors Wei-Chieh Huang, Ruey-Hsing Chou, Chun-Chin Chang, Chien-Yi Hsu, Yu-Chen Ku, Hsiu-Fen Huang, Yi-Chieh Chen, Po-Hsun Huang
Format Journal Article
LanguageChinese
Published 台灣 中華民國心臟學會 01.09.2017
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MEDLINE
Myocardial infarction
SCI
Scopus
Systemic inflammatory response syndrome
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Summary:Background: Convincing evidence suggests that inflammatory biomarkers are associated with an increased risk among patients with acute myocardial infarction (AMI). However, the impact of systemic inflammatory response (SIRS) on one-year clinical outcomes remains uncertain. Herein we investigated the impact of SIRS on one-year mortality and major adverse cardiovascular events (MACE) in patients with AMI. Methods: We conducted a retrospective study that enrolled patients admitted due to AMI and who received coronary artery intervention from January 2012 to June 2014. SIRS was defined according to standard criteria as having two or more of the following: (1) body temperature ＜ 36 or ＞ 38 C, (2) heart rate ＞ 90 beats per minute, (3) respiratory rate ＞ 20, or (4) white blood cell count ＜ 4000/mm3 or ＞ 12,000/mm3. The primary endpoint was one-year mortality. The secondary endpoint was a one-year MACE, including revascularization, AMI, and stroke. Results: A total of 330 AMI patients were enrolled in the study, and 1
ISSN:1011-6842