二苯甲醯基甲烷經由小鼠肝臟微粒體酵素作用之代謝途徑研究

• Published in: 藥物食品分析 Vol. 13; no. 3; pp. 284 - 288
• Main Authors: 林娟娟(Lin, Chuan-chuan), 魏國晉(Wei, Guor-jien), 黃茂端(Huang, Mou-tuan), 何其儻(Ho, Chi-tang)
• Format: Journal Article
• Language: Chinese
• Published: 台灣 衛生福利部食品藥物管理署 01.09.2005
• Subjects: 7,12-dimethylbenz[a]anthracene; 7,12-二甲基苯并蔥; Dibenzoylmethane; Mammary tumorigenesis; MEDLINE; Mouse liver microsomes; NADPH-dependent cytochrome P450 enzymes; NADPH-相關細胞色素代謝酵素; Reductive metabolite; SCIE; Scopus; 二苯甲醯基甲烷; 小鼠肝臟微粒體; 還原型代謝產物

Dibenzoylmethane (DBM), a curcumin-related β-diketone analogue, has been reported to exhibit a remarkable inhibitory effect on 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumorigenesis in Sencar mice. Investigation of the underlying mechanisms of DBM in the prevention of mammary tumorigene...