黃芩之傳統煎劑與濃縮製劑市場品中黃芩苷、黃芩苷元和漢黃芩素含量之分析與比較

• Published in: 藥物食品分析 Vol. 9; no. 3; pp. 145 - 149
• Main Authors: 賴妙英(Lai, Miao-ying), 陳忠川(Chen, Chung-chuan), 徐素蘭(Hsiu, Su-lan), 李珮端(Lee Chao, Pei-dawn)
• Format: Journal Article
• Language: Chinese
• Published: 台灣 衛生福利部食品藥物管理署 01.09.2001
• Subjects: Baicalein; Baicalin; Commercial extract; Decoction; MEDLINE; SCIE; Scopus; Scutellariae Radix; Wogonin; 傳統煎劑; 漢黃芩素; 濃縮製劑; 黃芩; 黃芩苷; 黃芩苷元
• ISSN: 1021-9498

Baicalin, Baicalein and wogonin are bioactive flavonoids ofScutellariae Radix. In order to compare the contents of baicalin. baicalein andwogonin between traditional decoction and commercial extract, ten crude drugsand ten commercial extracts of Scutellariae Radix were purchased from themarket. High performance liquid chromatographic method was used for simultaneousassay of these flavonoid constituents. The separatin was performed on anInertsil ODS-2 column with acetonitrile -0.005% phosphoric acid (36:64, v/v) asmobile phase at a flow-rate of 1.0 mL/min and detection at 270 nm, and ethylparaben was used as the internal standard. This method is applicable for theroutine quality control of the crude drug and commercial extract of ScutellariaeRadix. The results indicated that the contents of baicalin, baicalein andwogonin in traditional decoctions of each gram of Scutellariae Radix were 62.7± 4.6 mg, 5.5 ± 0.2 mg and 1.7 ± 0.1 mg, whereas those in each gram ofcommercial extracts were 82.3 ± 8.5 mg, 15.0 ± 2.0 m