Asymmetric Chemical Synthesis of (R)- and (S)-Citramalate in High Enantiomeric Purity

Both enantiomers of dimethyl 2-acety1citramalate have been asymmetrically synthesized in over 96% enantiomeric excess and good overall chemical yield (500/0)from 2-keto-1,3-oxathianes 1a, and 1b.

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Bibliographic Details
Published inCroatica Chemica Acta Vol. 58; no. 4; p. 647
Main Authors Frye, Stephen V, Eliel, Ernest L
Format Paper
LanguageEnglish
Published Hrvatsko kemijsko društvo 06.03.1986
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Summary:Both enantiomers of dimethyl 2-acety1citramalate have been asymmetrically synthesized in over 96% enantiomeric excess and good overall chemical yield (500/0)from 2-keto-1,3-oxathianes 1a, and 1b.
Bibliography:178051
ISSN:0011-1643
1334-417X