Polyunsaturated fatty acid deficiency reverses effects of alcohol on mitochondrial energy metabolism

• Published in: Journal of hepatology Vol. 41; no. 5; pp. 721 - 9
• Main Authors: Piquet, Marie-Astrid, Roulet, Michel, Nogueira, Véronique, Filippi, Céline, Sibille, Brigitte, Hourmand-Ollivier, Isabelle, Pilet, Marianne, Rouleau, Vincent, Leverve, Xavier M
• Format: Journal Article
• Language: English
• Published: Elsevier 01.11.2004
• Subjects: Animal Feed; Animals; Dietary Fats; Energy Metabolism; Fatty Acids, Unsaturated; Liver Diseases, Alcoholic; Male; Mitochondria, Liver; Oxygen Consumption; Rats; Rats, Wistar

BACKGROUND/AIMS: Polyunsaturated fatty acids (PUFA) deficiency is common in patients with alcoholic liver disease. The suitability of reversing such deficiency remains controversial. The aim was to investigate the role played by PUFA deficiency in the occurrence of alcohol-related mitochondrial dysf...