X-ray tomography crystal characterization: Growth monitoring

In this study, we present a new approach for the growth monitoring of crystals using micro X-ray computed tomography (XCT). This technique allows us to track the evolution of the total crystal volume and surface in real time, and to calculate the growth rate. By segmenting the 3D XCT images using a...

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Bibliographic Details
Published inJournal of crystal growth Vol. 612
Main Authors Hypolite, Gautier, Vicente, Jérôme, Taligrot, Hugo, Moulin, Philippe
Format Journal Article
LanguageEnglish
Published Elsevier 15.06.2023
Subjects
Chemical and Process Engineering
Engineering Sciences
A1
Crystal characterization A1
Growth monitoring
C
C segmentation
segmentation
X-ray tomography A1
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Summary:In this study, we present a new approach for the growth monitoring of crystals using micro X-ray computed tomography (XCT). This technique allows us to track the evolution of the total crystal volume and surface in real time, and to calculate the growth rate. By segmenting the 3D XCT images using a robust method, we are able to extract detailed information about the crystals, such as their number, volume, diameter, and sphericity. Additionally, we determine the growth rates of individual crystal faces. Our method has the potential to greatly benefit the pharmaceutical and chemical industries, as it provides insight into the structural parameters of crystals during growth, which is crucial for optimization and control.
ISSN:0022-0248
DOI:10.1016/j.jcrysgro.2023.127187