An Absence of Non-specific Immune Response towards para -Sulphonato-calix[ n ]arenes

The effects of para-Sulphonato-calix[4]arene, para-Sulphonato-calix[6]arene and para-Sulphonato-calix[8]arene on the activation of NADPH oxidase in neutrophils has been studied. All three molecules do not induce NADPH oxidase activation, and hence do not stimulate neutrophils. Measurement of cell vi...

Full description

Saved in:
Bibliographic Details
Published inJournal of Inclusion Phenomena and Macrocyclic Chemistry Vol. 55; pp. 353 - 357
Main Authors Paclet, Marie-Hélène, Rousseau, Cécile F, Campion, Yannick, Morel, Françoise, Coleman, Anthony W.
Format Journal Article
LanguageEnglish
Published Springer Verlag 01.06.2006
Subjects
Immunology
Life Sciences
calix[n]arenas
immune response
cell mortality
neutrophils
Online AccessGet full text

Cover

More Information
Summary:The effects of para-Sulphonato-calix[4]arene, para-Sulphonato-calix[6]arene and para-Sulphonato-calix[8]arene on the activation of NADPH oxidase in neutrophils has been studied. All three molecules do not induce NADPH oxidase activation, and hence do not stimulate neutrophils. Measurement of cell viability demonstrates that these three water-soluble calix[n]arene derivatives are not cytotoxic.
ISSN:0923-0750
1573-1111