The lysozyme of the starfish Asteriasrubens

On the basis of a partial N-terminal sequence, Jolle`s and Jolle`s [Jolle`s, J., & Jolle`s, P. (1975) Eur. J. Biochem. 54, 19–23] previously proposed that the lysozyme from the starfish Asterias rubens represents a new form of lysozyme, called type i (invertebrate) lysozyme. Indeed, it differed...

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Published inEuropean Journal of Biochemistry Vol. 271; pp. 237 - 242
Main Authors Bachali, Sana, Bailly, Xavier, Jolles, Jacqueline, Jolles, Pierre, S. Deutsch, Jean
Format Journal Article
LanguageEnglish
Published Wiley 2004
Subjects
Biochemistry, Molecular Biology
Life Sciences
Structural Biology
lysozyme
struc- ture
DNA
starfish
invertebrates
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Summary:On the basis of a partial N-terminal sequence, Jolle`s and Jolle`s [Jolle`s, J., & Jolle`s, P. (1975) Eur. J. Biochem. 54, 19–23] previously proposed that the lysozyme from the starfish Asterias rubens represents a new form of lysozyme, called type i (invertebrate) lysozyme. Indeed, it differed from both the types c (chicken) and g (goose) known in other animals, as well as from plant and phage lysozymes. Recently, several proteins belonging to the same family have been isolated from protostomes. Here we report the com- plete mature protein sequence and cDNA sequence of the lysozyme from Asterias. These sequences vindicate the previously proposed homology between the starfish, a deuterostome, and protostome lysozymes. In addition, we present a structural analysis that allows us to postulate upon the function of several conserved residues.
ISSN:0014-2956
1432-1327
DOI:10.1046/j.1432-1033.2003.03915.x