Trakya Üniversitesi Saglik Arastirma ve Uygulama Merkezi Mikrobiyoloji Laboratuvari Toxoplasma gondii Seroloji Test Sonuçlarinin Retrospektif Olarak Degerlendirilmesi/Retrospective Evaluation of Toxoplasma gondii Serological Test Results of Trakya University Health Center for Medical Research and Practice

• Published in: Türkiye parazitolojii dergisi Vol. 47; no. 1; p. 6
• Main Authors: Eryildiz, Canan, Çakmakçi, Berrak Kaplan, Aldi, Feza Irem, Sakru, Nermin
• Format: Journal Article
• Language: English
• Published: Galenos Yayinevi Tic. Ltd 01.03.2023
• Subjects: Analysis; Immunoglobulin G; Resveratrol
• ISSN: 1300-6320; 2146-3077
• DOI: 10.4274/tpd.galenos.2022.25743

Amaç: Toxoplasma gondii (T. gondii) tüm dünyada dagilim gösteren zorunlu hücre içi bir parazittir. Tanida yaygin olarak T. gondii'ye özgü antikorlarin arastirildigi serolojik testler kullanilmaktadir. Bu çalismanin amaci; Trakya Üniversitesi Saglik Arastirma ve Uygulama Merkezi Seroloji Laboratuvari'na gönderilen anti-T. gondii IgG, anti-T. gondii IgM ve anti-T. gondii IgG avidite testi sonuçlarinin retrospektif olarak degerlendirilmesidir. Yöntemler: Ocak 2012-Aralik 2021 tarihleri arasinda laboratuvarimiza gönderilen ve enzim baglantili floresans testi veya elektrokemilüminesans immunoassay yöntemi ile çalisilan anti-T. gondii IgM, anti-T. gondii IgG ve T. gondii IgG avidite test sonuçlari retrospektif olarak laboratuvar kayitlarindan degerlendirildi. Bulgular: Anti-T. gondii IgG arastirilan 18.659 serum örneginden 5.127'si (%27,5), anti-T. gondii IgM arastirilan 21.108 serum örneginden 721'i (%3,4) pozitif olarak bulundu. IgG avidite testi çalisilan 593 serum örneginin 206'sinda (%34,7) düsük, 118'inde (%19,9) ara deger, 269'unda (%45,4) ise yüksek avidite degerleri saptandi. Sonuç: Çalismamiz, literatür verileriyle uyumlu olarak, bölgemizde seropozitifligin ihmal edilemeyecek derecede yüksek oldugunu göstermektedir. Özellikle dogurganlik çagindaki kadinlardaki süpheli klinik durumlarda T. gondii mutlaka akla getirilmelidir. Anahtar Kelimeler: Toxoplasma gondii, seroprevalans, Trakya, Türkiye Objective: Toxoplasma gondii (T. gondii) is an obligate intracellular parasite distributed worldwide. Serological tests investigating antibodies specific to T. gondii are widely used in diagnosis. The aim of this study was to evaluate the results of anti-T. gondii IgG, anti-T. gondii IgM, and anti-T. gondii IgG avidity tests, which were sent to the Serology Laboratory of Trakya University Health Center for Medical Research and Practice, retrospectively. Methods: Anti-T. gondii IgM, anti-T. gondii IgG, and anti-T. gondii IgG avidity tests were studied by enzyme-linked fluorescent assay or electrochemiluminescence immunoassay method between January 2012 and December 2021. The test results were evaluated retrospectively from laboratory records. Results: Of 18,659 serum samples were studied for anti-T. gondii IgG, 5,127 (27.5%) samples were positive, whereas 721 (3.4%) of 21,108 samples were positive for anti-T. gondii IgM. Of the 593 serum samples tested for IgG avidity, 206 (34.7%) samples had low avidity, 118 (19.9%) had borderline, and 269 (45.4%) had high avidity. Conclusion: Our study, compatible with other studies, showed that seropositivity is high in our region, which is not negligible. Especially in women of reproductive age population, T. gondii should be considered in suspected clinical cases. Keywords: Toxoplasma gondii, seroprevalence, Thrace, Turkey