An evaluation of attention deficit hyperactivity disorder and specific learning disorder in children born to diabetic gravidas: a case control study/Diyabetik gebelerden dogan cocuklarin dikkat eksikligi hiperaktivite bozuklugu ve ozgul ogrenme guclugu acisindan degerlendirilmesi: Olgu kontrol calismasi

• Published in: Anadolu psikiyatri dergisi Vol. 20; no. 4; p. 442
• Main Authors: Akaltun, Ismail, Yapca, Omer Erkan, Ayaydin, Hamza, Kara, Tayfun
• Format: Journal Article
• Language: Turkish
• Published: Anadolu Psikiyatri Dergisi 01.08.2019
• Subjects: Attention deficit hyperactivity disorder; Batteries; Blood glucose; Child health; Childhood mental disorders; Diabetes mellitus; Fasting; Gestational diabetes; Hyperactivity; Insulin; Learning disorders; Medical research; Pregnancy; Pregnant women; Schizophrenia; Type 2 diabetes
• ISSN: 1302-6631
• DOI: 10.5455/apd.10445

Objective: Children born after risky pregnancies are known to have an increased disposition to neurodevelopmental disorders. The purpose of our study was to investigate the relationship between diabetic pregnancy and attention deficit hyperactivity disorder (ADHD) and specific learning disorder (SLD). Methods: One hundred thirty-seven children of mothers with diabetic pregnancies and 128 children of mothers without a history of diabetic pregnancy were enrolled. Forty-nine of the case group had a history of insulin-dependent diabetes mellitus (IDDM) and 88 of gestational diabetes mellitus (GDM). All participants were evaluated using The Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children (6-18) (K-SADS PL), the Wechsler Intelligence Scale for Children-Revised (WISC-R), and the SLD Battery. The results were then subjected to statistical analysis. Results: A statistically significant difference was determined between the case and control groups in terms of levels of diagnosis of ADHD and SLD. Significant differences were determined between verbal/performance/total IQ scores when IDDM and GDM were compared with the control group. When the IDDM and GDM subgroups were compared among themselves, no significant difference was determined between verbal/performance/total IQ scores. Significant variation was observed between the IDDM and GDM groups in terms of ADHD and SLD diagnoses. IQ scores decreased as fasting blood sugar increased in all parameters. Conclusion: Significantly, more diagnoses of ADHD and SLD were observed in children born to diabetic mothers compared to those of non-diabetic mothers. Further, wide-ranging studies on the subject of the effect of diabetic pregnancy and blood sugar control on infant neurodevelopmental disorders are now needed. (Anatolian Journal of Psychiatry 2019; 20(4):442-448) Keywords: attention deficit hyperactivity disorder, specific learning disorder, diabetic pregnant, mental health, child, neurodevelopmental disorders Amac: Riskli hamileliklerden dogan cocuklarda norogelisimsel bozukluklara egilimin arttigi bilinmektedir. Calismamizda diyabetik gebelik ile dikkat eksikligi hiperaktivite bozuklugu (DEHB) ve ozgul ogrenme guclugu (OOG) arasindaki iliskiyi arastirmayi amacladik. Yontem: Bu calismaya, annelerinde diyabetik gebeligi olan 137 cocuk ile annesinde diyabetik gebelik oykusu olmayan 128 cocuk alindi. Olgu gurubunda 49 katilimcinin insuline bagimli diyabetes mellitus (IBDM), 88 katilimcinin gestasyonel diyabetes mellitus (GDM) oykusu vardi. Tum katilimcilar, Okul Cagi Cocuklari icin Duygulanim Bozukluklari ve Sizofreni Gorusme Cizelgesi-Simdi ve Yasam Boyu Sekli (618) (K-SADS PL), Wechsler Cocuklar icin Zeka Testi (WISC-R), OOG Bataryasi ile degerlendirildi. Elde edilen sonuclar istatistiksel olarak karsilastirildi. Bulgular: Olgu ve kontrol gruplari arasinda DEHB ve OOG tanisi oranlari arasinda istatistiksel olarak anlamli fark vardi. IBDM ve GDM ile kontrol grubu karsilastirildiginda sozel/performans/ toplam IQ puanlari arasinda anlamli fark saptandi. IBDM ve GDM kendi iclerinde karsilastirildiginda sozel/performans/toplam IQ puanlari arasinda anlamli fark saptanmadi. IDDM ve GDM gruplari arasinda DEHB ve OOG tanilari arasinda anlamli fark oldugu goruldu. Tum parametrelerde aclik kan sekeri (AKS) arttikca IQ puanlarinda dusus oldugu gorulmustur Sonuc: Diyabetik gebelerden dogan cocuklarda DEHB ve OOG tanilarinin diyabetik olmayan gebelerden dogan cocuklara gore daha fazla oldugu goruldu. Diyabetik gebeligin ve kan sekeri kontrolunun, bebek lerin norogelisimsel bozukluklar uzerine etkisi konusunda daha genis kapsamli calismalara gerek vardir. (Anadolu Psikiyatri Derg 2019; 20(4):442-448) Anahtar sozcukler: Dikkat eksikligi hiperaktivite bozuklugu, ozgul ogrenme bozuklugu, diyabetik gebe, ruh sagligi, cocuk, norogelisimsel bozukluklar