Synthesis of [.sup.188ReX

Radiochemically pure [.sup.188ReX(CO).sub.5] (X = Cl, Br, and I) were prepared for the first time by high-pressure carbonylation of .sup.188ReO.sub.4.sup.- with carbon monoxide in an aqueous solution in the presence of halide ions at 210 °C. The complexes were isolated at the n.c.a. level from the r...

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Published inJournal of radioanalytical and nuclear chemistry Vol. 308; no. 3; p. 1039
Main Authors Miroslavov, A. E, Alekseev, I. E, Tyupina, M. Yu, Lumpov, A. A, Stepanova, E. S, Kol'tsov, V. V, Sidorenko, G. V
Format Journal Article
LanguageEnglish
Published Springer 01.06.2016
Subjects
Carbon monoxide
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Summary:Radiochemically pure [.sup.188ReX(CO).sub.5] (X = Cl, Br, and I) were prepared for the first time by high-pressure carbonylation of .sup.188ReO.sub.4.sup.- with carbon monoxide in an aqueous solution in the presence of halide ions at 210 °C. The complexes were isolated at the n.c.a. level from the reaction mixture by gas-phase transport with carbon monoxide at a high pressure. The procedure allows obtaining the target compounds in any appropriate solvent (aqueous and nonaqueous), which may open new synthetic prospects for the development of novel therapeutic radiopharmaceuticals.
ISSN:0236-5731
DOI:10.1007/s10967-015-4558-7