Association of Body Mass Index with Outcomes in Patients with Atrial Fibrillation: Analysis from the

Background: Atrial fibrillation (AF) accounts for the majority of arrhythmias affecting adults. It is associated with an increased mortality and various complications. Obesity being a major risk factor of cardiovascular and metabolic diseases including AF has always been connected to the overall bur...

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Bibliographic Details
Published inVascular health and risk management Vol. 20; p. 89
Main Authors Laswi, Bushra, Ibdah, Rashid, Alenazi, Lina Ib, Rawashdeh, Sukaina, Alghzawi, Ahmad Abdalmajeed, Atoum, Amer K, Al Omary, Anwar Y, Hammoudeh, Ayman
Format Journal Article
LanguageEnglish
Published Dove Medical Press Limited 31.03.2024
Subjects
Analysis
Anticoagulants (Medicine)
Atrial fibrillation
Body mass index
Care and treatment
Hypertension
Middle East
Mortality
Obesity
Patient outcomes
Prognosis
Risk factors
Type 2 diabetes
Middle East
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Summary:Background: Atrial fibrillation (AF) accounts for the majority of arrhythmias affecting adults. It is associated with an increased mortality and various complications. Obesity being a major risk factor of cardiovascular and metabolic diseases including AF has always been connected to the overall burden of AF, but its role in the development of AF complications remains unclear. Our study aims to evaluate the impact of obesity on the complications of AF in Jordanian patients to establish a proper prognosis since studies regarding this topic in the Middle East are scant. Methods: This study analyzed data from the Jordanian AF study (JoFib), which enrolled Jordanians with AF. Clinical characteristics were compared among patients who developed complications and those who did not. A binary logistic regression analysis was conducted to identify factors associated with AF complications development. Results: 1857 patients were enrolled. There was no significant difference in BMI value between patients who developed complications and those who did not. Male sex, old age, hypertension, diabetes mellitus, and higher risk scores were associated with increased odds of developing complications. The oral anticoagulant use was found to be protective. Smoking had no significant effect on odds of complications. Conclusion: The study concludes that increased BMI is not significantly associated with a reduced risk of developing AF complications. Further research with longer follow-up and larger sample sizes is needed to confirm these results. Keywords: atrial fibrillation, clinical outcome, complications, Middle East, obesity, paradox
ISSN:1178-2048