Greener synthesis of ZnO and Ag-ZnO nanoparticles using

To investigate the physical and biological properties of inspired ZnO nanoparticles (NPs), Ag-ZnO heterostructures. Nanoparticles were characterized using ultraviolet-visible and infrared spectroscopy, x-ray diffraction, high resolution electron microscopy, ζ potential and thermo-gravimetric analysi...

Full description

Saved in:
Bibliographic Details
Published inNanomedicine (London, England) Vol. 14; no. 6; pp. 655 - 673
Main Authors Hameed, Safia, Khalil, Ali T, Ali, Muhammad, Numan, Muhammad, Khamlich, Saleh, Shinwari, Zabta K, Maaza, Malik
Format Journal Article
LanguageEnglish
Published Future Medicine Ltd 01.02.2019
01.03.2019
Subjects
Ag-ZnO
antileishmanial
antimicrobial
antioxidant
enzyme inhibition
nanocomposite
nanoparticles
nanoscosmaceutical
ZnO
Online AccessGet full text

Cover

More Information
Summary:To investigate the physical and biological properties of inspired ZnO nanoparticles (NPs), Ag-ZnO heterostructures. Nanoparticles were characterized using ultraviolet-visible and infrared spectroscopy, x-ray diffraction, high resolution electron microscopy, ζ potential and thermo-gravimetric analysis etc. Ag-ZnO-NPs indicated slightly higher antimicrobial potential then ZnO-NPs. Good antileishmanial (IC = 246 μg/ml for Ag-ZnO; 341 μg/ml for ZnO) and antioxidant potential while moderate enzyme inhibition is reported. 2, 2-Diphenyl 1-picrylhydrazyl radical scavenging of Ag-ZnO was higher relative to ZnO-NPs. Nanocosmaceutical formulation of nanoparticles indicated stable antimicrobial performance. Biosynthesized nanoparticles indicated interesting biological properties and should be subjected to further research to establish their pharmacological relevance.
ISSN:1743-5889
1748-6963
DOI:10.2217/nnm-2018-0279