In vitro examination of some biological activities of glycoprotein antigens of the PI3 virus

On the basis of the results obtained we have reached the following conclusions: (1) The fusional activity of separated activated glycoprotein antigens of the PI3 virus (++) is twice as high as the fusional activity of the same ones within complete viral particles (+). (2) The hemagglutinating activi...

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Published inMikrobiologija (Moskva) Vol. 34; no. 1
Main Authors Milic, N.S, Gadjanski-Omerovic, G, Asanin, R, Markovic, B.S, Drekic, D, Krnjajic, D, Kostovic, M, Crvak, B. (Faculty of Veterinary Medicine, Belgrade (Yugoslavia))
Format Journal Article
LanguageEnglish
Published 1997
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Summary:On the basis of the results obtained we have reached the following conclusions: (1) The fusional activity of separated activated glycoprotein antigens of the PI3 virus (++) is twice as high as the fusional activity of the same ones within complete viral particles (+). (2) The hemagglutinating activity of the samples of separated glycoprotein subunits (512 HJ/0.1 ml) is twice higher than in the samples of complete purified PI3 viruses (256 HJ/0.1 ml). (3) Our methods for purification and separation of glycoprotein antigens from outer envelopes of the PI1 virus enable us to preserve and increase the biological activities of immunologically significant H, N and F.
Bibliography:L73
1998000418
ISSN:0581-1538