Overexpression of the BRIP1 ameliorates chemosensitivity to cisplatin by inhibiting Rac1 GTPase activity in cervical carcinoma HeLa cells

• Main Authors: Liu, Yu, Hong LiauthorDepartment of Gynaecology and Obstetrics, Xi'an XD Group Hospital, Xi'an 710077, Shaanxi, China, Rui ZhangauthorMethadone Maintenance Treatment Clinic, Xi'an Mental Health Center, Xi'an 710061, Shaanxi, China, Huimin DangauthorDepartment of Traditional Chinese Medicine, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, Shaanxi, China, Ping SunauthorDepartment of Gynaecology and Oncology, Shaanxi Provincial Tumor Hospital, Xi'an 710065, Shaanxi, China, Lin ZouauthorDepartment of Gynaecology and Oncology, Shaanxi Provincial Tumor Hospital, Xi'an 710065, Shaanxi, China, Yongtong ZhangauthorDepartment of Radiotherapy, Shaanxi Provincial Tumor Hospital, Xi'an 710065, Shaanxi, China, Yanmei GaoauthorDepartment of Radiotherapy, Shaanxi Provincial Tumor Hospital, Xi'an 710065, Shaanxi, China, Yuqin HuauthorDepartment of Combination of Traditional Chinese and Western Medicine, Shaanxi Provincial Tumor Hospital, Xi'an 710061, Shaanxi, China
• Format: Journal Article
• Language: English
• Published: 2015
• Subjects: adenosinetriphosphatase; aggression; angiogenesis; antineoplastic activity; apoptosis; ATCC; BACH1; BRIP1; carcinogenesis; cDNA; cell viability; Cervical cancer; Chemosensitivity; Cisplatin; DNA; DNA helicases; DNA repair; drug therapy; FBS; FITC; GAPDH; GDS; gene overexpression; GST; GTP; guanosinetriphosphatase; mRNA; MTT; MVD; PBS; plasmids; PVDF; Rac1; ROS; RT-PCR; SDS-PAGE; SNPs; TEM; uterine cervical neoplasms