Synthesis and antifilarial activity of N-4-4-alkoxy-3-(dialkylamino)methylphenylamino-2-pyrimidinyl-N'-phenylguanidines

N-[4-[[4-alkoxy-3-[(dialkylamino)methyl]phenyl]amino]-2-pyrimidinyl]-N'-phenylguanidines, synthesis, antifilarial activity against adult Litomosoides carinii but lacked activity against L. carinii microfilariae or adult Brugia pahangi

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Bibliographic Details
Published inJournal of medicinal chemistry Vol. 26; no. 9; pp. 1258 - 1267
Main Authors Angelo, M, Ortwine, D, Worth, D, Werbel, L.M, McCall, J.W
Format Journal Article
LanguageEnglish
Published 1983
Subjects
Brugia pahangi
Litomosoides carinii
Treatment and control
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Summary:N-[4-[[4-alkoxy-3-[(dialkylamino)methyl]phenyl]amino]-2-pyrimidinyl]-N'-phenylguanidines, synthesis, antifilarial activity against adult Litomosoides carinii but lacked activity against L. carinii microfilariae or adult Brugia pahangi
ISSN:0022-2623
1520-4804