Naturally occurring variation in the restriction map of the Army region of Drosophila melanogaster

The restriction maps of 85 alleles of the Amy region of Drosophila melanogaster from natural populations were surveyed. A subset of these were also scored for allozyme phenotype and adult enzyme activity of alpha-amylase. Large insertions were found in 12% of the alleles in 15-kb region surroundingt...

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Published inGenetics (Austin) Vol. 119; no. 3; pp. 619 - 629
Main Authors Langley, C.H, Shrimpton, A.E, Yamazaki, T, Miyashita, N, Matsuo, Y, Aquadro, C.F
Format Journal Article
LanguageEnglish
Published 1988
Subjects
alleles
allozymes
Drosophila melanogaster
enzyme activity
genetic code
genetic variation
genomics
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Summary:The restriction maps of 85 alleles of the Amy region of Drosophila melanogaster from natural populations were surveyed. A subset of these were also scored for allozyme phenotype and adult enzyme activity of alpha-amylase. Large insertions were found in 12% of the alleles in 15-kb region surroundingthe two transcriptional units of the duplicated Amy locus. The low freguencies at which each of these large insertions were found are consistent with earlier reports of variation in other loci. Four small deletions were found in the region 5' to the Amy genes. Each was also rare in the population. Restriction site variation provided an estimate of per nucleotide heterozygosity of 0.0006. Several statistically significant linkage disequilibria were observed between four polymorphic restriction sites and the allozymes. Adult alpha-amylase activity was correlated with the allozymes and with the polymorphism at one restriction site close to the transcriptional units.
ISSN:0016-6731
1943-2631