Evidence for multiple anthelmintic resistance of gastrointestinal nematodes in sheep in coastal Kenya

This Report compares the efficacies of three anthelmintics, each belonging to one of the broad spectrum groups. It also identifies the genera of resistant worms through larval culture. The study was conducted on a commercial farm where anthelmintics had been used intensively. The results show clearl...

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Bibliographic Details
Main Authors Mwamachi, D.M, Audho, J.O, Magadi, M, Reynolds, L, Baker, R.L
Format Conference Proceeding
LanguageEnglish
Published Small Ruminant Collaborative Research Support Programme 1993
Subjects
DIGESTIVE SYSTEM DISEASES
DRUG THERAPY
KENYA
NEMATODES
PEST RESISTANCE
SHEEP
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Summary:This Report compares the efficacies of three anthelmintics, each belonging to one of the broad spectrum groups. It also identifies the genera of resistant worms through larval culture. The study was conducted on a commercial farm where anthelmintics had been used intensively. The results show clearly that gastrointestinal nematodes in sheep at Diani Estate are resistance to ivermectin and fenbendazole, and that injectable ivermectin appeared more effective than the oral form. Resistance to levamisole appears to be developing, which is surprising given the short period that this drug has been in use at Diani. The predominant nematode genus at Diani is haemonchus contortus.
Bibliography:http://hdl.handle.net/10568/50495