Molecular interactions of β-(1→3)-glucans with their receptors
β-(1→3)-Glucans can be found as structural polysaccharides in cereals, in algae or as exo-polysaccharides secreted on the surfaces of mushrooms or fungi. Research has now established that β-(1→3)-glucans can trigger different immune responses and act as efficient immunostimulating agents. They const...
Saved in:
Published in | Molecules 6 (20), 9745-9766. (2015) |
---|---|
Main Authors | , , , , |
Format | Publication |
Language | English |
Published |
2015
|
Subjects | |
Online Access | Get more information |
Cover
Loading…
Summary: | β-(1→3)-Glucans can be found as structural polysaccharides in cereals, in algae or as exo-polysaccharides secreted on the surfaces of mushrooms or fungi. Research has now established that β-(1→3)-glucans can trigger different immune responses and act as efficient immunostimulating agents. They constitute prevalent sources of carbons for microorganisms after subsequent recognition by digesting enzymes. Nevertheless, mechanisms associated with both roles are not yet clearly understood. This review focuses on the variety of elucidated molecular interactions that involve these natural or synthetic polysaccharides and their receptors, i.e., Dectin-1, CR3, glycolipids, langerin and carbohydrate-binding modules. |
---|---|
Bibliography: | http://prodinra.inra.fr/record/312361 http://prodinra.inra.fr/ft/C9F85393-8928-454B-9EB6-9E83DA87C937 10.3390/molecules20069745 |