Anti-inflammatory and Anti-allergic Effect of Extracts from Organic Soybean

• Published in: Korean Journal of Organic Agriculture Vol. 19; no. 2
• Main Authors: Chung, E.K., Kyung Hee University, Yongin, Republic of Korea, Seo, E.H., Biowells, Chuncheon, Republic of Korea, Park, J.H., Biowells, Chuncheon, Republic of Korea, Shim, H.R., Biowells, Chuncheon, Republic of Korea, Kim, K.H., Gangwon-do Agricultural Research and Extention Services, Chuncheon, Republic of Korea, Lee, B.R., Hallym University, Chuncheon, Republic of Korea
• Format: Journal Article
• Language: Korean
• Published: 01.06.2011
• Subjects: anti-allergic effects; anti-apoptotic effects; anti-inflammatory effects; anti-oxidative effects; organic soybean; SOJA; soybean extracts; SOYBEANS
• ISSN: 1229-3571

This study was carried out to investigate the biological effects of organic soybean extracts. Cellular and molecular analysis was performed to determine anti-oxidative, anti-inflammatory, anti-apoptotic, and anti-inflammatory effects of soybean extracts. First, we obtained various solvent extracts of soybean such as water, ethanol, and methanol. Molecular and cellular analysis were performed with 0.1 mg/ml concentration of each solvent extracts. The results of anti-oxidative, anti-inflammatory and anti-apoptotic effects of organic soybean extracts were prominent. However, organic soybean extracts were not observed in anti-allergic effects determined by releasing histamine from rat mast cell line, RBL-2H3. Conclusively, organic soybean suppress inflammatory responses. In addition, organic soybean could be applied as a functional food ingredient for treatment of chronic inflammation, asthma, and atopic dermatitis with enhanced anti-inflammatory activities.